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In an early-eighteenth-century legal contest on Chappaquiddick Island, Massachusetts, an Indian leader, Jacob Seeknout, appealed a ruling that under-mined his political authority. Seeknout's lawyer, Benjamin Hawes, crafted an argument that intertwined the sexual legitimacy of Seeknout's ancestors with his political legitimacy; at the same time, Hawes also linked Indians'collective chastity as a "nation" to their sovereign status. This paper examines the economic, religious, criminal, and historical contexts of this argument, exploring the history of Indians'conjugal practices and their reinvention as the criminal acts of fornication. The case illustrates some of the diverse sources of early American law, links between these legal structures and colonialism, and the importance for scholars of attending to the local level in exploring the power of colonial law to shape new racial identities.  相似文献   
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2,5-Dimethoxy-4-bromoamphetamine (DOB) is one of the potent hallucinogenic phenylalkylamines, whose ingestion has already caused several deaths reported all over the world. However, there is unsufficient information on DOB properties based on controlled pharmacokinetic studies available. The aim of this study was to clarify the distribution profile of DOB and its phenolic metabolite 2-methoxy-5-hydroxy-4-bromoamphetamine (2M5H4BA) in blood and biological tissues of experimental rats. The rats were administered a 20 mg/kg dose of DOB·HCl by oral ingestion or subcutaneous injection. Plasma and brain, liver and lung tissues were collected at 0.5, 1, 2, 4, 8, 16, and 32 h after dosing (three animals per time point). The samples were prepared by a liquid–liquid extraction procedure and the extracts were assayed by GC–MS. After per oral application, DOB peak plasma level of 320 ng/mL was reached after one-hour post dosing as well as 2M5H4BA peak concentration of 203 ng/mL. A rapid phase of DOB absorption, 2M5H4BA formation and their tissue distribution during the first two hours after application were followed by a slow decrease rate of the elimination process until 32 h. After subcutaneous application, high plasma levels of the unchanged parent drug and relatively reduced formation of its metabolite 2M5H4BA were observed. DOB maximum plasma concentration of 1143 ng/mL was reached after one-hour post application, whereas its metabolite peak level after 8 h was 213 ng/mL. The concentration profiles of both compounds in plasma after per oral and subcutaneous administration revealed the existence of significant first pass effect after per oral administration that significantly affected DOB bioavailability. DOB tissue concentrations exceeded plasma and the highest values were found in the lungs, where drug accumulation occurred with prolonged retention till 32 h after subcutaneous dose. Although the plasma/tissue transfer was more effective for the lipophilic parent drug than for its hydroxylated metabolite 2M5H4BA, the metabolite tissue levels were significant. The hallucinogenic potential of 2M5H4BA appearing in brain remains unclear as nothing is known about its pharmacological activity at present.  相似文献   
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Wiebke Marie Junk 《管理》2019,32(2):313-330
Lobbying access to policy discussions determines how political interests are voiced and potentially exert influence. This article addresses whether access to the national legislature and the media favors umbrella organizations, which represent interests of their member groups. It theorizes that the role of umbrellas goes beyond signaling a large individual membership or constituency of people, but that umbrellas are distinct in transmitting interests from other organizations. This function is expected to be valuable in exchanges with legislators who seek efficiency, input legitimacy, and policy implementation, but less valuable in the media arena. Using a new data set on lobbying by 286 groups on 12 issues in the United Kingdom and Germany, the article serves support for this theory: Umbrellas enjoy higher legislative access, but lower media access than groups without member organizations, irrespective of their individual membership or claimed constituency. The findings have implications for how we understand and study political representation.  相似文献   
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The rhetoric of then U.S. President‐elect Donald Trump and Philippines' President Rodrigo Duterte had triggered a shift in global political discourse (Greene, 2016 ). This study examines their responses on three similar crises: disrespectful remarks towards women, associations with controversial political figures, and remarks threatening geopolitical relations. Data from prestige publications, Washington Post (U.S.) and the Philippine Daily Inquirer, were analyzed during the acute stage of each crisis. Findings showed that both men employed confusing strategy combinations in their crisis responses. Despite incoherent application and contradictory strategies, they survived threats to their image as evidenced by poll results. New strategies (diversion and logorrhea) and a strategy amplifier (machismo) were uncovered. These strategies tapped on ambiguity and were found to be successfully employed in a post‐truth landscape. This study builds on Benoit's ( 2006 ) argument that “any attempt by a president to repair a damaged image … clearly merits scholarly attention” (p. 138).  相似文献   
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Spirituality/religiosity is hypothesized to promote positive adjustment among adolescents. The goals of this study were to assess the unique and joint associations between two dimensions of spirituality/religiosity—institutional and personal—and a range of domains of psychosocial adjustment (intrapersonal well-being, quality of parent–child relationship, substance use, and academic orientation) and to evaluate the direction of effects in these associations. Participants included 803 predominately Canadian-born adolescents (53 % female) from Ontario, Canada, who completed a survey in grade 11 and grade 12. At the concurrent level, higher personal spirituality/religiosity consistently and uniquely predicted more positive adjustment in terms of well-being, parental relationship, and academic orientation. Higher institutional spirituality/religiosity uniquely and consistently predicted lower substance use, particularly when personal spirituality/religiosity also was high. With regard to the direction of effects (i.e., longitudinal associations), institutional spirituality/religiosity predicted lower future substance use. The results imply that the personal and institutional dimensions of spirituality/religiosity may be associated differentially with psychosocial adjustment, and it may be only in the domain of substance use that spirituality/religiosity predicts change in behavior over time.  相似文献   
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This article discusses the complexities associated with adopting a not-knowing stance in Child and Youth Care practice. By highlighting some of the challenges, it also clarifies the distinctions between practitioner lack of knowing how to proceed and an intentional, uncertain attitude when working with children, youth and families. Recommendations or caveats are provided if a practitioner chooses to adopt this kind of orientation to practice.  相似文献   
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This article presents an analytic approach to the study of gender meaning in an academic context. In the presentation empirical material from an interview study among 29 Danish male and female university students is applied. The analytic approach is based on the conception of gender meaning as a culturally constructed phenomenon in continuous process. Current gender meaning is seen as a construction based on the idea of coherence between the gendered sign on the body and a variety of components including sexual and professionally related aspects. The connections between body sign and the components as well as among the components themselves are a continuous goal of negotiation processes among the male and female students.  相似文献   
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